Features of morphological changes in the colon and anterior abdominal wall tissues after xenopericardium implantation 

Vladislav E. Kiselev, Postgraduate student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: kiselyov999@mail.ru
Valeriy I. Nikol'skiy, Doctor of medical sciences, professor, professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: nvi61@yandex.ru
Konstantin I. Sergatskiy, Doctor of medical sciences, associate professor, professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia); coloproctologist of the department of coloproctology, Penza Regional Clinical Hospital named after N.N. Burdenko (28 Lermontova street, Penza, Russia), E-mail: sergatsky@bk.ru
Mariya G. Fedorova, Candidate of medical sciences, associate professor, head of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: fedorovamerry@gmail.com
Ekaterina V. Titova, Candidate of medical sciences, associate professor, associate professor of the sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: kineta@yandex.ru 

Background. Currently, in order to perform the prevention and treatment of hernias of the anterior abdominal wall, along with the use of synthetic materials, biological implants are used. Materials and research methods. We had the opportunity to conduct a morphological study of the tissues of the abdominal wall and colon in one clinical observation 5 months after the preventive installation of a xenopericardial plate in a patient to prevent paracolostomy hernia during an emergency colostomy. During the reconstructive operation, the leading section of the large intestine together with the aponeurosis site of the external oblique muscle of the abdomen and the xenopericardium implanted during the initial operation were sent for histological examination. Results. In the zone of implantation of the xenopericardial plate to the aponeurosis of the external oblique muscle of the abdomen, it was found that the xenopericardium is integrated into its own tissues. At the same time, a dense interweaving of collagen and elastic fibers of the connective tissue with xenopericardial fibers was noted. In the zone of implantation to the wall of the colon, it was found that the xenopericardium is embedded in the structure of the organ, and its fibers are located in the thickness of the intestinal wall. Conclusions. The study allows us to state that the location of the biological prosthesis directly at the wall of the hollow organ is safe and is not accompanied by any complications. 

parastomal hernia, ventral hernia, xenopericardium, biological prosthesis, longterm results 

Kiselev V.E., Nikol'skiy V.I., Sergatskiy K.I., Fedorova M.G., Titova E.V. Features of morphological changes in the colon and anterior abdominal wall tissues after xenopericardium implantation. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2023;(4):53–64. (In Russ.). doi: 10.21685/2072-3032-2023-4-6